Survey of Phytochemical Composition and Biological Effects of Three Extracts from a Wild Plant (Cotoneaster nummularia Fisch et Mey.): A Potential Source for Functional Food Ingredients and Drug Formulations

Publication Type:Journal Article
Year of Publication:2014
Authors:G. Zengin, Uysal, A., Gunes, E., Aktumsek, A.
Journal:Plos OnePlos OnePlos One
Date Published:Nov 19
ISBN Number:1932-6203
Accession Number:WOS:000345533200134
Keywords:antioxidant activities, aqueous extracts, essential oil, ferulic acid, herbal teas, in-vitro, l., medicinal-plants, total phenolic content, turkey

This study was focused on the analysis of the phenolic content, antioxidant, antibacterial, anti-cholinesterase, anti-tyrosinase, anti-amylase and anti-glucosidase activity of three solvent extracts from Cotoneaster nummularia. Moreover, water extract was tested in terms of mutagenic/anti-mutagenic effects. The antioxidant activities of these extracts were evaluated by DPPH, ABTS, O-2, metal chelating, phosphomolybdenum, beta-carotene/linoleic acid, ferric and cupric reducing power assays. Enzyme inhibitory activities were also examined with colorimetric methods. Generally, methanol and water extracts exhibited excellent biological activities. These extracts were rich in phenolic and flavonoid content. Furthermore, Cotoneaster extracts indicated appreciable antibacterial properties against human pathogen strains. HPLC analysis showed that ferulic acid, chlorogenic acid, (-) - epicatechin and (+)-catechin were the major phenolics in extracts tested. These data offer that these extracts from C. nummularia may be considered as a potential source of biological agents for developing functional foods or drug formulations.

Short Title:Plos OnePlos One
Alternate Journal:Plos One
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